ID
1150

Nadolol (four isomers)

COMPOUND IDENTIFICATION

Molecular Weight
309.400
Formula
C17H27O4N
Property
Basic

CHROMATOGRAM

Nadolol (four isomers)

ANALYTICAL REPORT

Column Trade Name
(Column size / Particle size)
CHIRALPAK® AD-H
(4.6 x 250 mm 5 µm)
Chromatographic Mode Polar Phase
Mobile Phase Composition acetonitrile / 2-propanol / ethanolamine = 95 / 5 / 0.1
Flow rate (mL/min) 1 Temperature (℃) 25
Injection Volume (µL) 0.01 (mg) Sample Concentration
Detection UV-VIS 230 nm
Elution Order
No. Rt K'
1 6.7 1.20
2 9.6 2.20
3 12.1 3.10
4 45.5 14.10
Alpha Value Resolution
1 - 2 1.80 5.60
2 - 3 1.40 5.00
3 - 4 4.60 17.50