ID
1489

Afatinib

COMPOUND IDENTIFICATION

Molecular Weight
485.937
Formula
C24H25N5O3FCl
Property
Basic
Afatinib

Compound name

Afatinib

CHROMATOGRAM

Afatinib

ANALYTICAL REPORT

Column Trade Name
(Column size / Particle size)
CHIRALPAK® IE
(4.6 x 250 mm 5 µm)
Chromatographic Mode Normal Phase
Mobile Phase Composition methanol / methyl tert-butyl ether / diethylamine = 80 / 20 / 0.1
Flow rate (mL/min) 0.7 Temperature (℃) 15
Injection Volume (µL) 0.01 (mg) Sample Concentration
Detection UV-VIS 340 nm
Elution Order
No. Rt K'
1 15.2 2.55
2 16.9 2.94
Alpha Value Resolution
1 - 2 1.15 2.49