ID
1496

Bortezomib

COMPOUND IDENTIFICATION

Molecular Weight
384.236
Formula
C19H25N4O4B
Property
Basic
Bortezomib

Compound name

Bortezomib

CHROMATOGRAM

Bortezomib

ANALYTICAL REPORT

Column Trade Name
(Column size / Particle size)
CHIRALPAK® AD-3
(4.6 x 250 mm 3 µm)
Chromatographic Mode Normal Phase
Mobile Phase Composition n-heptane / ethanol / 2-propanol / acetic acid = 90 / 5 / 5 / 0.1
Flow rate (mL/min) 1 Temperature (℃) 25
Injection Volume (µL) 0.005 (mg) Sample Concentration
Detection UV-VIS 270 nm
Elution Order API, SS, SR, RR
No. Rt K'
1 8.2 1.73
2 9.8 2.26
3 11.3 2.78
4 13.7 3.57
Alpha Value Resolution
1 - 2 1.30 3.21
2 - 3 1.23 2.73
3 - 4 1.28 3.63