COMPOUND IDENTIFICATION
Compound name
- Dolutegravir
CHROMATOGRAM
ANALYTICAL REPORT
|
Column Trade Name (Column size / Particle size) |
CHIRALPAK® IF-3 (4.6 x 250 mm 3 µm) |
|---|---|
| Chromatographic Mode | Reverse Phase |
| Mobile Phase Composition | 10mM KPF6 aq. pH2.0 / methyl tert-butyl ether / acetonitrile = 40 / 5 / 55 |
| Flow rate (mL/min) | 1 | Temperature (℃) | 25 |
|---|---|---|---|
| Injection Volume (µL) | 0.01 (mg) | Sample Concentration | |
| Detection | UV-VIS 260 nm | ||
| Elution Order | Enantiomer, API | ||
| No. | Rt | K' |
|---|---|---|
| 1 | 12.3 | 3.09 |
| 2 | 15.5 | 4.15 |
| Alpha Value | Resolution | |
|---|---|---|
| 1 - 2 | 1.34 | 3.96 |