ID
1662

Lamivudine (containing the enantiomeric impurity)

COMPOUND IDENTIFICATION

Molecular Weight
229.256
Formula
C8H11O3SN3
Property
Basic

CHROMATOGRAM

Lamivudine (containing the enantiomeric impurity)

ANALYTICAL REPORT

Column Trade Name
(Column size / Particle size)
CHIRALPAK® IC-3
(4.6 x 250 mm 3 µm)
Chromatographic Mode Normal Phase
Mobile Phase Composition acetonitrile / diethylamine = 100 / 0.1
Flow rate (mL/min) 1.0 Temperature (℃) 25
Injection Volume (µL) 0.02 (mg) Sample Concentration
Detection UV-VIS 260 nm
Elution Order
No. Rt K'
1 8.9 -
2 10.1
3 17.6
4 21.6
Alpha Value Resolution
1 - 2 - 2.60
2 - 3 3.30
3 - 4 8.00