ID
184

Argatroban (enriched and separated from its (21S)-diastereomer)

COMPOUND IDENTIFICATION

Molecular Weight
522.659
Formula
C24H38N6SO5
Property
Amphoteric

CHROMATOGRAM

Argatroban (enriched and separated from its (21S)-diastereomer)

ANALYTICAL REPORT

Column Trade Name
(Column size / Particle size)
CHIRALPAK® IA-3
(4.6 x 150 mm 3 µm)
Chromatographic Mode Normal Phase
Mobile Phase Composition n-hexane / 2-propanol / trifluoroacetic acid / diethylamine = 95 / 5 / 0.4 / 0.3
Flow rate (mL/min) 0.7 Temperature (℃) 25
Injection Volume (µL) Sample Concentration
Detection UV-VIS 330 nm
Elution Order
No. Rt K'
1 9.1 2.55
2 11.1 3.33
Alpha Value Resolution
1 - 2 1.31 2.63