ID
400

Nadolol (four isomers)

COMPOUND IDENTIFICATION

Molecular Weight
309.400
Formula
C17H27O4N
Property
Basic

CHROMATOGRAM

Nadolol (four isomers)

ANALYTICAL REPORT

Column Trade Name
(Column size / Particle size)
CHIRALPAK® IA
(4.6 x 250 mm 5 µm)
Chromatographic Mode Normal Phase
Mobile Phase Composition n-heptane / ethanol / diethylamine = 85 / 15 / 0.1
Flow rate (mL/min) 1 Temperature (℃) 25
Injection Volume (µL) 0.01 (mg) Sample Concentration
Detection UV-VIS 230 nm
Elution Order
No. Rt K'
1 10.4 2.50
2 12.1 3.00
3 16.7 4.60
4 27.2 8.10
Alpha Value Resolution
1 - 2 1.20 2.70
2 - 3 1.50 6.30
3 - 4 1.70 8.10