ID
673

Nadolol (four isomers)

COMPOUND IDENTIFICATION

Molecular Weight
309.400
Formula
C17H27O4N
Property
Basic

CHROMATOGRAM

Nadolol (four isomers)

ANALYTICAL REPORT

Column Trade Name
(Column size / Particle size)
CHIRALPAK® AD-H
(4.6 x 250 mm 5 µm)
Chromatographic Mode Normal Phase
Mobile Phase Composition n-heptane / ethanol / ethanolamine = 80 / 20 / 0.1
Flow rate (mL/min) 1 Temperature (℃) 25
Injection Volume (µL) 0.01 (mg) Sample Concentration
Detection UV-VIS 230 nm
Elution Order
No. Rt K'
1 10.6 2.50
2 17.3 4.80
3 21.9 6.30
4 64.7 20.60
Alpha Value Resolution
1 - 2 1.90 10.00
2 - 3 1.30 5.00
3 - 4 3.30 18.40