APPLICATION ID 1504

Cobicistat

COMPOUND IDENTIFICATION

Compound Name Cobicistat
Cobicistat

CHROMATOGRAM

Chromatogram

ANALYTICAL REPORT

Column Trade Name

Column Size / Particle Size

CHIRALPAK® IE-3

250 x 4.6mm / 3µm

Mobile Phase Composition

n-hexane / ethanol / diethylamine = 65 / 35 / 0.1

Chromatographic Mode

Normal Phase
Primary screening solvent (Immobilised CSP)

Flow rate (ml/min)

1

Injection amount (mg)

0.01

Temperature (°C)

40

Pressure (MPa)

Detection

UV 238 nm

Elution order

RRR, SSS, API, SRS

No.

Rt

K’

1

16.63

4.54

2

18.69

5.23

3

20.49

5.83

4

24.29

7.1

Alpha Value

Resolution

1 - 2

1.15

2.11

2 - 3

1.11

2.44

3 - 4

1.22

4.31

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