APPLICATION ID 1506

Darunavir

COMPOUND IDENTIFICATION

Compound Name Darunavir
Darunavir

CHROMATOGRAM

Chromatogram

ANALYTICAL REPORT

Column Trade Name

Column Size / Particle Size

CHIRALPAK® IE-3

250 x 4.6mm / 3µm

Mobile Phase Composition

n-hexane / ethanol / diethylamine = 70 / 30 / 0.1

Chromatographic Mode

Normal Phase
Primary screening solvent (Immobilised CSP)

Flow rate (ml/min)

1

Injection amount (mg)

0.03

Temperature (°C)

25

Pressure (MPa)

Detection

UV 265 nm

Elution order

RS, SS, API, RR

No.

Rt

K’

1

14.94

3.98

2

16.38

4.46

3

17.84

4.95

4

22.41

6.47

Alpha Value

Resolution

1 - 2

1.12

1.72

2 - 3

1.11

1.79

3 - 4

1.31

4.34

To the top of the page