ID
1520

Lurasidone

COMPOUND IDENTIFICATION

Molecular Weight
492.675
Formula
C28H36N4O2S
Property
Basic
Lurasidone

Compound name

Lurasidone

CHROMATOGRAM

Lurasidone

ANALYTICAL REPORT

Column Trade Name
(Column size / Particle size)
CHIRALPAK® IE-3
(4.6 x 250 mm 3 µm)
Chromatographic Mode Normal Phase
Mobile Phase Composition n-hexane / ethanol / tetrahydrofuran / diethylamine = 80 / 10 / 10 / 0.1
Flow rate (mL/min) 1 Temperature (℃) 25
Injection Volume (µL) 0.0075 (mg) Sample Concentration
Detection UV-VIS 320 nm
Elution Order t1,t2=API, t3,t4,t5,t6,t7=Enantiomer
No. Rt K'
1 10.5 2.21
2 11.0 2.68
3 15.4 4.14
4 16.1 4.36
5 18.7 5.25
6 20.3 5.77
7 25.3 7.44
8 34.4 10.48
Alpha Value Resolution
1 - 2 1.07 1.46
2 - 3 1.55 9.47
3 - 4 1.05 1.14
4 - 5 1.20 4.28
5 - 6 1.10 2.24
6 - 7 1.29 5.63
7 - 8 1.41 7.22