APPLICATION ID 1538

Sitagliptin (racemic)

COMPOUND IDENTIFICATION

Compound Name Sitagliptin (racemic)
Sitagliptin (racemic)

CHROMATOGRAM

Chromatogram

ANALYTICAL REPORT

Column Trade Name

Column Size / Particle Size

CHIRALPAK® IE

250 x 4.6mm / 5µm

Mobile Phase Composition

methyl tert-butyl ether / acetonitrile / methanol / diethylamine = 80 / 10 / 10 / 0.1

Chromatographic Mode

Normal Phase
Primary screening solvent (Immobilised CSP)

Flow rate (ml/min)

1

Injection amount (mg)

0.03

Temperature (°C)

25

Pressure (MPa)

Detection

UV 264 nm

Elution order

No.

Rt

K’

1

6.44

1.15

2

7.78

1.59

Alpha Value

Resolution

1 - 2

1.39

4.18

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