APPLICATION ID 1656

Afatinib

COMPOUND IDENTIFICATION

Compound Name Afatinib
Afatinib

CHROMATOGRAM

Chromatogram

ANALYTICAL REPORT

Column Trade Name

Column Size / Particle Size

CHIRALPAK® IE

250 x 4.6mm / 5µm

Mobile Phase Composition

methyl tert-butyl ether / methanol / diethylamine = 20 / 80 / 0.1

Chromatographic Mode

Normal Phase

Flow rate (ml/min)

0.7

Injection amount (mg)

Temperature (°C)

15

Pressure (MPa)

Detection

UV 340 nm

Elution order

No.

Rt

K’

1

15.2

2

17

Alpha Value

Resolution

1 - 2

2.5

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