APPLICATION ID 248

Sitagliptin (racemic)

COMPOUND IDENTIFICATION

Compound Name Sitagliptin (racemic)
Sitagliptin (racemic)

CHROMATOGRAM

Chromatogram

ANALYTICAL REPORT

Column Trade Name

Column Size / Particle Size

CHIRALPAK® IC-3

150 x 4.6mm / 3µm

Mobile Phase Composition

n-hexane / 2-propanol / ethylenediamine = 50 / 50 / 0.1

Chromatographic Mode

Normal Phase
Primary screening solvent (Immobilised CSP)

Flow rate (ml/min)

1

Injection amount (mg)

Temperature (°C)

40

Pressure (MPa)

Detection

UV 265 nm

Elution order

No.

Rt

K’

1

6.92

2.84

2

8.41

3.67

Alpha Value

Resolution

1 - 2

1.29

2.62

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