APPLICATION ID 433

Sertraline (enriched)

COMPOUND IDENTIFICATION

Compound Name Sertraline (enriched)
Sertraline (enriched)

CHROMATOGRAM

Chromatogram

ANALYTICAL REPORT

Column Trade Name

Column Size / Particle Size

CHIRALPAK® IA

250 x 4.6mm / 5µm

Mobile Phase Composition

n-hexane / ethanol / methanol / diethylamine = 98 / 1 / 1 / 0.1

Chromatographic Mode

Normal Phase
Primary screening solvent (Immobilised CSP)

Flow rate (ml/min)

1

Injection amount (mg)

Temperature (°C)

25

Pressure (MPa)

Detection

UV 270 nm

Elution order

No.

Rt

K’

1

5.42

0.81

2

6.03

1.01

3

7.06

1.35

4

7.81

1.6

Alpha Value

Resolution

1 - 2

1.25

3.6

2 - 3

1.34

5

3 - 4

1.18

3.2

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