APPLICATION ID 434

Solifenacin (containing two pairs of enantiomers)

COMPOUND IDENTIFICATION

Compound Name Solifenacin (containing two pairs of enantiomers)
Solifenacin (containing two pairs of enantiomers)

CHROMATOGRAM

Chromatogram

ANALYTICAL REPORT

Column Trade Name

Column Size / Particle Size

CHIRALPAK® IC

250 x 4.6mm / 5µm

Mobile Phase Composition

n-hexane / 2-propanol / ethanol / diethylamine = 60 / 25 / 15 / 0.1

Chromatographic Mode

Normal Phase
Primary screening solvent (Immobilised CSP)

Flow rate (ml/min)

1

Injection amount (mg)

Temperature (°C)

30

Pressure (MPa)

Detection

UV 220 nm

Elution order

No.

Rt

K’

1

7.81

1.6

2

9.09

2.03

3

11.51

2.84

4

14.83

3.94

Alpha Value

Resolution

1 - 2

1.27

3.7

2 - 3

1.4

5.7

3 - 4

1.39

6

To the top of the page